Tuesday, March 20, 2012

Genetic Profiling for Breast Cancer Treatment

Our paper, CLIME, appeared in Journal of the American Statistical Association last year.  It is always amazing to me that how science can help shape the future.  Part of the paper employed a mathematical model to study if we can predict the outcome of a breast cancer patient based on her genetic profile.  The prediction performance is interestingly good.
Average (SD) performance of classifying breast cancer treatment outcomes over 100 out-of-sample runs.
Both the sensitivity and specificity are high (>=75%).  The R package for the CLIME method is here on CRAN, and I will provide an update very soon.

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